North Node Institute of Neuroscience and Epigenetics
Advancing Non-Invasive, Brain-Centered Approaches to Healing and Human Optimization
Our Mission
To establish a new medical framework grounded in neuroplasticity, epigenetic modulation, and the brain's ability to regulate biological function through measurable cognitive and physiological mechanisms.
About Us
The North Node Institute of Neuroscience and Epigenetics (NNINE) is a private, accreditation-eligible research institution dedicated to advancing non-invasive, brain-centered approaches to healing and human optimization. Our groundbreaking work focuses on reversing chronic diseases, treatment-resistant mental health disorders, and neurodegenerative decline using evidence-based protocols that do not rely on pharmacological or surgical interventions.
Our work combines advanced neuroimaging, gene expression profiling, and cognitive science to create validated, replicable interventions capable of inducing long-term physiological change. NNINE operates at the intersection of translational neuroscience and clinical application—building a bridge between cutting-edge academic research and accessible, real-world healing tools.
Our Approach
Neuroplasticity-Based Healing
Leveraging the brain's natural ability to reorganize and form new neural connections for therapeutic outcomes.
Epigenetic Modulation
Using targeted interventions to influence gene expression and cellular function without altering DNA structure.
Measurable Outcomes
Employing advanced neuroimaging and biomarker analysis to track and validate therapeutic progress.
Evidence-Based Protocols
Developing rigorously tested, replicable interventions grounded in scientific methodology.
Non-Invasive Treatment
Focusing on healing approaches that avoid pharmaceutical dependence and surgical interventions.
Personalized Medicine
Tailoring interventions based on individual neurobiological profiles and genetic markers.
Principal Investigator
Shifa Maryam
Distinction-Honored Neuroscientist, King's College London
Founder & Principal Investigator
Shifa Maryam is a distinction-honored Neuroscientist from King's College London and the visionary Founder and Principal Investigator at NNINE. Her groundbreaking work is dedicated to advancing a new paradigm of medicine—one that leverages the brain's intrinsic neurobiological capabilities to reverse chronic disease and restore health without invasive procedures or long-term pharmacological dependence.
Maryam's academic foundation in neuroplasticity, epigenetic modulation, and the biological basis of emotional trauma has informed her development of the NNINE Repatterning Technique (NRT™)—a proprietary, neuroscience-driven healing model that integrates advanced brain imaging, cognitive-emotional retraining, and gene expression tracking.
Her published research explores the link between subconscious emotional stress, dysregulated biological function, and chronic illness, proposing that targeted brain-state modulation can unlock measurable and repeatable healing outcomes. The NRT™ protocol is currently undergoing structured human-subject trials under the scientific guidance of an honorary advisory board composed of world-class researchers from institutions including Columbia University, Harvard Medical School, and Oxford University.